Socio-economic status linked to detection of congenital heart defects – Consumer Health News


MONDAY, May 17, 2021 (HealthDay News) – Lower socioeconomic quartile (SEQ), Hispanic ethnicity, and rural residence are associated with lower prenatal detection (PND) of congenital heart disease, particularly major artery transposition ( TGA), according to a study published online May 17 in Circulation.

Anita Krishnan, MD, of the Children’s National Heart Institute in Washington, DC, and her colleagues conducted a retrospective multicenter cohort study involving fetuses and infants with hypoplastic left heart syndrome (HLHS) or TGA with an initial assessment in a participating institution between 2012 and 2016. The authors examined associations of SEQ, type of insurance, race / ethnicity, rural residence, and distance of residence with PND from HLHS or TGA.

Data were included for 1,862 people (1,171 with HLHS [92 percent PND] and 691 with TGA [58 percent PND]) in 21 centers (19 in the United States). Researchers found that lower SEQ was associated with lower PND in HLHS and TGA in the United States, with the largest effect in lower SEQ of pregnancies with fetal TGA (risk ratios, 0.78 and 0.77 for quartiles 1 and 2, respectively, compared to quartile 4). A lower PND in TGA was also observed in association with Hispanic ethnicity (risk ratio, 0.85) and rural residence (risk ratio, 0.78).

“Although the results were not completely surprising and resonate with clinical experience, the strength of the associations was surprising,” Krishnan said in a statement.

Summary / Full Text (subscription or payment may be required)


Leave a Reply

Your email address will not be published.