Miraculous ‘polypill’ – made from 3 drugs – may reduce risk of heart disease: study

The study followed patients for an average of three years and produced conclusive results: patients taking the CNIC polypills had a 24% lower risk of all four events than patients taking the three separate drugs.

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Barcelona:Elderly patients with heart disease who took a ‘polypill’ combination of three different drugs had a lower risk of major cardiovascular events, according to a new study.
The study, published in the New England Journal of Medicine, showed that the ‘polypill’ effectively prevents secondary adverse cardiovascular events in people who have already had a heart attack, reducing cardiovascular mortality by 33% in this patient population. .

“The polypill, being a very simple strategy that combines three essential treatments for this type of patient, has proven itself because the improvement in compliance means that these patients receive better treatment and therefore have a lower risk of cardiovascular events. recurring,” said the researcher. Jose Maria Castellano of the Fundacion de Investigacion HM Hospitales.

For the study, presented at the Congress of the European Society of Cardiology in Spain, the team looked at 2,499 patients in seven European countries who had a history of type 1 myocardial infarction within the last six months and were aged over 75 or at least 65 with at least one risk factor, such as diabetes or mild or moderate kidney dysfunction.

The average age of the participants was 76 years old and 31% were women.

The study population included 77.9% hypertension, 57.4% diabetes and 51.3% smoking history.

The researchers analyzed the incidence of four major cardiovascular events: death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, and the need for emergency coronary revascularization (the restoration of blood flow through a coronary artery obstructed).

The study followed patients for an average of three years and produced conclusive results: patients taking the CNIC polypills had a 24% lower risk of all four events than patients taking the three separate drugs.

The results showed a relative reduction of 33%, from 71 patients in the group receiving standard treatment to just 48 in the polypill group.